Movement disorders and AIDS: a review

被引：68

作者：

Tse, W

Cersosimo, MG

Gracies, JM

Morgello, S

Olanow, CW

Koller, W

机构：

[1] CUNY Mt Sinai Sch Med, Dept Neurol, New York, NY 10029 USA

[2] Univ Buenos Aires, Dept Neurol, Buenos Aires, DF, Argentina

[3] Mt Sinai Med Ctr, Dept Pathol, New York, NY USA

来源：

PARKINSONISM & RELATED DISORDERS | 2004年 / 10卷 / 06期

关键词：

parkinsonism; AIDS; human immunodeficiency virus; movement disorders; dopamine; chorea;

D O I：

10.1016/j.parkreldis.2004.03.001

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Movement disorders are a potential neurologic complication of acquired immune deficiency syndrome (AIDS), and may sometimes represent the initial manifestation of HIV infection. Dopaminergic dysfunction and the predilection of HIV infection to affect subcortical structures are thought to underlie the development of movement disorders such as parkinsonism in AIDS patients. In this review, we will discuss the clinical presentations, etiology and treatment of the various AIDS-related hypokinetic and hyperkinetic movement disorders, such as parkinsonism, chorea, myoclonus and dystonia. This review will also summarize current concepts regarding the pathophysiology of parkinsonism in HIV infection. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：323 / 334

页数：12

共 93 条

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