Treatments to induce the nucleation and growth of apatite-like layers on polymeric surfaces and foams

被引:57
作者
Reis, RL
Cunha, AM
Fernandes, MH
Correia, RN
机构
[1] UNIV PORTO, FAC ENGN, DEPT MET ENGN, P-4099 OPORTO, PORTUGAL
[2] INST BIOMED ENGN, INEB, P-4050 OPORTO, PORTUGAL
[3] UNIV AVEIRO, DEPT CERAM & GLASS ENGN, P-3810 AVEIRO, PORTUGAL
关键词
D O I
10.1023/A:1018514107669
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
In this work, a bioactive glass is used as a percusor of calcium-phosphate (Ca-P) film deposition onto several polymer-based materials. Both bioinert (high molecular weight polyethylene, HMWPE), and biodegradable (corn starch-based blends, SEVA-C) polymers, unreinforced or reinforced with hydroxylapatite (HA), were coated by the very simple proposed route. Also polyurethane (PU) foams, with an open-cell structure, were mineralized by the proposed method. In fact, it was possible to induce the growth of the Ca-P films not only at the surface, but also in the bulk of the PU foam. These cellular materials are intended for cancel to us bo ne replacement applications. The morphology of the formed fi I ms was strongly dependent on the used substrate, its polar character, and on the presence of HA in its composition, as observed by SEM. Nevertheless, a well defined needle like structure was observed in all samples at high magnifications. The Ca:P ratios of the films were between 1.5 and 1.7, i.e. in the range of tricalcium phosphate-hydroxylapatite. Raman spectroscopy and thin-film x-ray diffraction (XRD) evidenced the formation of mostly amorphous calcium-phosphate films. After scraping the coating from the polymer surface and heat-treating the resulting powder at 1000 degrees C for 1 h, HA and beta-tricalcium phosphate (TCP) typical peaks were found on XRD patterns.
引用
收藏
页码:897 / 905
页数:9
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