Effectiveness of bronchial thermoplasty in severe asthma in "real life' patients compared with those recruited to clinical trials in the same centre

被引:29
作者
Bicknell, Stephen [2 ]
Chaudhuri, Rekha [1 ]
Lee, Nicola [2 ]
Shepherd, Malcolm [2 ]
Spears, Mark [2 ]
Pitman, Nick [2 ]
Cameron, Euan [2 ]
Cowan, Douglas [2 ]
Nixon, Julie [2 ]
Thompson, Joyce [2 ]
McSharry, Charles [3 ]
Thomson, Neil C. [2 ,3 ]
机构
[1] Gartnavel Royal Hosp, Dept Resp Med, Glasgow G12 OYN, Lanark, Scotland
[2] Univ Glasgow, Inst Infect Immun & Inflammat, Glasgow, Lanark, Scotland
[3] Univ Glasgow, Inst Infect Immun & Inflammat, Glasgow, Lanark, Scotland
关键词
asthma; bronchial thermoplasty; bronchoscopy; SAFETY;
D O I
10.1177/1753465815601332
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
100201 [内科学];
摘要
Published information on the effectiveness of bronchial thermoplasty (BT) for severe asthma in real life' patients is limited. We compared safety and efficacy outcomes 12 months post procedure in 10 clinic patients and 15 patients recruited to clinical trials of BT at the same centre. Baseline asthma severity was greater in the clinic group. Adverse events were similar. Clinical improvements occurred in 50% of the clinic patients compared with 73% of the research patients.
引用
收藏
页码:267 / 271
页数:5
相关论文
共 11 条
[1]
Oral Glucocorticoid-Sparing Effect of Mepolizumab in Eosinophilic Asthma [J].
Bel, Elisabeth H. ;
Wenzel, Sally E. ;
Thompson, Philip J. ;
Prazma, Charlene M. ;
Keene, Oliver N. ;
Yancey, Steven W. ;
Ortega, Hector G. ;
Pavord, Ian D. .
NEW ENGLAND JOURNAL OF MEDICINE, 2014, 371 (13) :1189-1197
[2]
How to: Bronchial thermoplasty in asthma [J].
Bicknell, Stephen ;
Chaudhuri, Rekha ;
Thomson, Neil C. .
BREATHE, 2014, 10 (01) :49-59
[3]
Effectiveness and Safety of Bronchial Thermoplasty in the Treatment of Severe Asthma A Multicenter, Randomized, Double-Blind, Sham-Controlled Clinical Trial [J].
Castro, Mario ;
Rubin, Adalberto S. ;
Laviolette, Michel ;
Fiterman, Jussara ;
Lima, Marina De Andrade ;
Shah, Pallav L. ;
Fiss, Elie ;
Olivenstein, Ronald ;
Thomson, Neil C. ;
Niven, Robert M. ;
Pavord, Ian D. ;
Simoff, Michael ;
Duhamel, David R. ;
McEvoy, Charlene ;
Barbers, Richard ;
ten Hacken, Nicolaas H. T. ;
Wechsler, Michael E. ;
Holmes, Mark ;
Phillips, Martin J. ;
Erzurum, Serpil ;
Lunn, William ;
Israel, Elliot ;
Jariour, Nizar ;
Kraft, Monica ;
Shargill, Narinder S. ;
Quiring, John ;
Berry, Scott M. ;
Cox, Gerard .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2010, 181 (02) :116-124
[4]
Asthma control during the year after bronchial thermoplasty [J].
Cox, Gerard ;
Thomson, Neil C. ;
Rubin, Adalberto S. ;
Niven, Robert M. ;
Corris, Paul A. ;
Siersted, Hans Christian ;
Olivenstein, Ronald ;
Pavord, Ian D. ;
McCormack, David ;
Chaudhuri, Rekha ;
Miller, John D. ;
Laviolette, Michel ;
Busse, W. ;
Schellenberg, R. ;
Slutsky, A. S. ;
Nair, P. ;
Goodwin, S. ;
Currie, K. ;
Bourbeau, J. ;
Houghton, F. ;
Patterson, N. ;
Metha, S. ;
Howard, J. ;
MacBean, L. ;
Martel, S. ;
Boulet, L. -P. ;
Morel, L. ;
Trepanier, L. ;
Bicknell, S. ;
Livingston, E. ;
Lafferty, J. ;
Prys-Picard, C. ;
Fletcher, G. ;
Higgins, B. ;
Small, T. ;
Foggo, B. ;
Berry, M. ;
Shaw, D. ;
Sheldon, N. ;
Barnes, N. ;
Watson, D. ;
Cardoso, P. G. ;
Soares, P. R. D. ;
Rasmussen, F. ;
Christensen, H. M. ;
Olsen, M. .
NEW ENGLAND JOURNAL OF MEDICINE, 2007, 356 (13) :1327-1337
[5]
Safety and Feasibility of Bronchial Thermoplasty in Asthma Patients with Very Severe Fixed Airflow Obstruction: A Case Series [J].
Doeing, Diana C. ;
Mahajan, Amit K. ;
White, Steven R. ;
Naureckas, Edward T. ;
Krishnan, Jerry A. ;
Hogarth, Douglas K. .
JOURNAL OF ASTHMA, 2013, 50 (02) :215-218
[6]
Safety and efficacy of bronchial thermoplasty in symptomatic, severe asthma [J].
Pavord, Ian D. ;
Cox, Gerard ;
Thomson, Neil C. ;
Rubin, Adalberto S. ;
Corris, Paul A. ;
Niven, Robert M. ;
Chung, Kian F. ;
Laviolette, Michel .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2007, 176 (12) :1185-1191
[7]
Safety of bronchial thermoplasty in patients with severe refractory asthma [J].
Pavord, Ian D. ;
Thomson, Neil C. ;
Niven, Robert M. ;
Corris, Paul A. ;
Chung, Kian Fan ;
Cox, Gerard ;
Armstrong, Brian ;
Shargill, Narinder S. ;
Laviolette, Michel .
ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY, 2013, 111 (05) :402-407
[8]
Bronchial thermoplasty for severe asthma [J].
Thomson, Neil C. ;
Bicknell, Stephen ;
Chaudhuri, Rekha .
CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY, 2012, 12 (03) :241-248
[9]
Long-term (5 year) safety of bronchial thermoplasty: Asthma Intervention Research (AIR) trial [J].
Thomson, Neil C. ;
Rubin, Adalberto S. ;
Niven, Robert M. ;
Corris, Paul A. ;
Siersted, Hans Christian ;
Olivenstein, Ronald ;
Pavord, Ian D. ;
McCormack, David ;
Laviolette, Michel ;
Shargill, Narinder S. ;
Cox, Gerard .
BMC PULMONARY MEDICINE, 2011, 11
[10]
Bronchial thermoplasty for moderate or severe persistent asthma in adults [J].
Torrego, Alfons ;
Sola, Ivan ;
Maria Munoz, Ana ;
Roqe i Figuls, Marta ;
Jose Yepes-Nunez, Juan ;
Alonso-Coello, Pablo ;
Plaza, Vicente .
COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2014, (03)