Patients with stages III and IV endometriosis have a poorer outcome of in vitro fertilization-embryo transfer than patients with tubal infertility

被引:81
作者
Azem, F
Lessing, JB
Geva, E
Shahar, A
Lerner-Geva, L
Yovel, I
Amit, A
机构
[1] Tel Aviv Sourasky Med Ctr, IVF ET Unit, Lis Matern Hosp, IL-61070 Tel Aviv, Israel
[2] Chaim Sheba Med Ctr, Dept Epidemiol, Tel Aviv, Israel
[3] Tel Aviv Univ, Sackler Fac Med, IL-69978 Tel Aviv, Israel
关键词
endometriosis; tubal infertility; IVF; pregnancy outcome;
D O I
10.1016/S0015-0282(99)00392-1
中图分类号
R71 [妇产科学];
学科分类号
100211 [妇产科学];
摘要
Objective: To evaluate the outcome of IVF in patients with stages III and IV endometriosis. Design: Retrospective study. Setting: The Sara Racine IVF Unit, Lis Maternity Hospital, Tel Aviv Sourasky Medical Center, Israel. Patient(s): Fifty-eight patients with stages III and IV endometriosis and 60 patients with tubal infertility. Intervention(s): IVF-ET for all couples. Main Outcome Measure(s): Fertilization, pregnancy, and birth rates. Result(s): The comparison between patients with endometriosis and those with tubal infertility indicated that the former had a poor IVF outcome in terms of reduced fertilization rate (40% vs. 70%), reduced pregnancy rate per cycle (10.6% vs. 22.4%), and reduced birth rate per cycle (6.7% vs. 16.6%). The differences were statistically significant. Conclusion(s): The results show an unfavorable outcome of IVF-ET in patients with endometriosis when compared with those who have tubal infertility. (C) 1999 by American Society for Reproductive Medicine.
引用
收藏
页码:1107 / 1109
页数:3
相关论文
共 9 条
[1]
*AM FERT SOC, 1985, FERTIL STERIL, V43, P351
[2]
ENDOMETRIOSIS 1991 - A DISCUSSION DOCUMENT [J].
AUDEBERT, A ;
BACKSTROM, T ;
BARLOW, DH ;
BENAGIANO, G ;
BROSENS, I ;
BUHLER, K ;
DONNEZ, J ;
EVERS, JLH ;
PELLICER, A ;
METTLER, L ;
RONNBERG, L ;
SMITH, SK ;
THOMAS, EJ .
HUMAN REPRODUCTION, 1992, 7 (03) :432-435
[3]
TRANSFER OF 6 OR MORE EMBRYOS IMPROVES SUCCESS RATES IN PATIENTS WITH REPEATED IN-VITRO FERTILIZATION FAILURES [J].
AZEM, F ;
YARON, Y ;
AMIT, A ;
YOVEL, I ;
BARAK, Y ;
PEYSER, MR ;
DAVID, MP ;
LESSING, JB .
FERTILITY AND STERILITY, 1995, 63 (05) :1043-1046
[4]
DMOWSKI WP, 1995, FERTIL STERIL, V63, P535
[5]
JONES HW, 1984, FERTIL STERIL, V42, P826
[6]
MAHADEVAN MM, 1983, FERTIL STERIL, V40, P755
[7]
ENDOMETRIOSIS - A STAGE BY STAGE ANALYSIS - THE ROLE OF IN-VITRO FERTILIZATION [J].
OLIVENNES, F ;
FELDBERG, D ;
LIU, HC ;
COHEN, J ;
MOY, F ;
ROSENWAKS, Z .
FERTILITY AND STERILITY, 1995, 64 (02) :392-398
[8]
OUTCOME OF PATIENTS WITH ENDOMETRIOSIS IN ASSISTED REPRODUCTION - RESULTS FROM IN-VITRO FERTILIZATION AND OOCYTE DONATION [J].
SIMON, C ;
GUTIERREZ, A ;
VIDAL, A ;
DELOSSANTOS, MJ ;
TARIN, JJ ;
REMOHI, J ;
PELLICER, A .
HUMAN REPRODUCTION, 1994, 9 (04) :725-729
[9]
WARDLE PG, 1985, LANCET, V2, P236