Studies on gel tears

被引：4

作者：

Amin, PD

Bhogte, CP

Deshpande, MA

机构：

[1] Univ. Dept. of Chemical Technology, Pharmaceutical Section, University of Bombay, Matunga

来源：

DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY | 1996年 / 22卷 / 07期

关键词：

D O I：

10.3109/03639049609063231

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Artificial tear substitutes, namely gel tears, were formulated and evaluated in the treatment of keratoconjunctivitis sicca. A preservative efficacy test was performed to evaluate the most suitable preservative for the gel tears. The gel tears were subjected to varying stability conditions and assessed for various parameters, viz pH, viscosity, clarity, extrudability, and sterility. Eye irritation studies were performed on albino rabbits using the Draize technique. Clinical trials were conducted on normal volunteers and volunteers with mild to moderate conditions of keratoconjunctivitis sicca.

引用

页码：735 / 739

页数：5