Distribution of the meningococcal insertion sequence IS1301 in clonal Lineages of Neisseria meningitidis

被引：13

作者：

Hilse, R

Stoevesandt, J

Caugant, DA

Claus, H

Frosch, M

Vogel, U

机构：

[1] Univ Wurzburg, Inst Hyg & Mikrobiol, D-97080 Wurzburg, Germany

[2] Med Hsch Hannover, Inst Med Mikrobiol, D-30625 Hannover, Germany

[3] Natl Inst Publ Hlth, WHO, Collaborating Ctr Reference & Res Meningococci, N-0403 Oslo, Norway

来源：

EPIDEMIOLOGY AND INFECTION | 2000年 / 124卷 / 02期

关键词：

D O I：

10.1017/S0950268899003647

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

The distribution of the meningococcal insertion sequence IS1301 was analysed in 496 strains of different serogroups and clonal lineages of Neisseria meningitidis, and in 64 neisserial strains other than N. meningitidis. IS1301 was found in meningococci, but not in apathogenic Neisseria sp. and Neisseria gonorrhoeae. The copy numbers of IS1301 varied between 2 and 17 per genome. IS1301 positive strains were mostly found among the serogroups 29E, W135, X, and Y. Clonal lineages of serogroup A, B, and C meningococci associated with epidemic meningococcal disease were rarely positive for IS1301.

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页码：337 / 340

页数：4

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