2,2-Dimethyl-2,3-dihydrofuran, a new substrate for intermolecular asymmetric Heck reactions

被引：42

作者：

Hennessy, AJ ^{[1
]}

Malone, YM ^{[1
]}

Guiry, PJ ^{[1
]}

机构：

[1] Univ Coll Dublin, Dept Chem, Dublin 4, Ireland

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 51期

关键词：

D O I：

10.1016/S0040-4039(99)01980-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

2,2-Dimethyl-2,3-dihydrofuran is tested as a new substrate for the intermolecular asymmetric Heck reaction. Phenylation proceeded in enantioselectivities of up to 98% ee with Pd-0 complexes of diphenylphosphinoferrocenyloxazoline ligands. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：9163 / 9166

页数：4

共 23 条

[1] Identification of the effective palladium(0) catalytic species generated in situ from mixtures of Pd(dba)(2) and bidentate phosphine ligands. Determination of their rates and mechanism in oxidative addition [J].