Diazonamide synthesis studies: Use of Negishi coupling to fashion diazonamide-related biaryls with defined axial chirality

被引：37

作者：

Feldman, KS ^{[1
]}

Eastman, KJ ^{[1
]}

Lessene, G ^{[1
]}

机构：

[1] Penn State Univ, Dept Chem, University Pk, PA 16802 USA

来源：

ORGANIC LETTERS | 2002年 / 4卷 / 20期

关键词：

D O I：

10.1021/ol026694t

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] The syntheses of a bis indole and an indole salicylate with the required axial chirality for diazonamide A are reported. Atropselectivity in these biaryl systems is enforced by an sp(3) stereogenic center in a lactone tether in both cases.

引用

页码：3525 / 3528

页数：4

共 32 条

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