Transition metal complexes in organic synthesis.: Part 65:: Iron-mediated synthesis of carazostatin, a free radical scavenger from Streptomyces chromofuscus, and O-methylcarazostatin

被引：29

作者：

Knölker, HJ ^{[1
]}

Hopfmann, T ^{[1
]}

机构：

[1] Tech Univ Dresden, Inst Organ Chem, D-01069 Dresden, Germany

来源：

TETRAHEDRON | 2002年 / 58卷 / 44期

关键词：

carazostatin; Diels-Alder reaction; cyclization;

D O I：

10.1016/S0040-4020(02)01180-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Highly efficient syntheses of the free radical scavenger carazostatin and its O-methyl derivative are described using cyclohexa-1,3-diene and 2-heptyl-4-methoxy-3-methylaniline as starting materials and iron-mediated oxidative cyclizations as key-steps. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：8937 / 8945

页数：9

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