Acanthamoeba:: biology and increasing importance in human health

被引：645

作者：

Khan, Naveed Ahmed ^{[1
]}

机构：

[1] Univ London Birkbeck Coll, Sch Biol & Chem Sci, London WC1E 7HX, England

来源：

FEMS MICROBIOLOGY REVIEWS | 2006年 / 30卷 / 04期

关键词：

Acanthamoeba; encephalitis; keratitis; epidemiology; pathogenesis; disease;

D O I：

10.1111/j.1574-6976.2006.00023.x

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Acanthamoeba is an opportunistic protozoan that is widely distributed in the environment and is well recognized to produce serious human infections, including a blinding keratitis and a fatal encephalitis. This review presents our current understanding of the burden of Acanthamoeba infections on human health, their pathogenesis and pathophysiology, and molecular mechanisms associated with the disease, as well as virulence traits of Acanthamoeba that may be targets for therapeutic interventions and/or the development of preventative measures.

引用

页码：564 / 595

页数：32

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