Bioactive norlignan glucosides from Curculigo capitulata

被引：35

作者：

Chang, WL

Su, MJ

Lee, SS

机构：

[1] NATL TAIWAN UNIV,COLL MED,SCH PHARM,TAIPEI 100,TAIWAN

[2] NATL TAIWAN UNIV,COLL MED,INST PHARMACOL,TAIPEI 100,TAIWAN

来源：

JOURNAL OF NATURAL PRODUCTS | 1997年 / 60卷 / 02期

关键词：

D O I：

10.1021/np9604902

中图分类号：

Q94 [植物学];

学科分类号：

071001 [植物学];

摘要：

Chemical investigation of Curculigo capitulata yielded two new norlignans, (+)-(1R,2S)- and (-)-(1S,2S)-1-O-butylnyasicosides (1, 2), and the known nyasicoside (3) from the BuOH-soluble fraction of the rhizomes. An alternative study devoid of n-BuOH yielded two additional novel norlignans, 3 ''-dehydroxynyasicoside (4) and 1-O-methylnyasicoside (5), in addition to 3. The pharmacological studies indicated that 1 and 3 possessed potent activity against ouabain-induced arrhythmia in the heart preparations of guinea pig.

引用

页码：76 / 80

页数：5

共 7 条

[1]

RESEARCH ON AFRICAN MEDICINAL-PLANTS .25. THE (1R,2S) ABSOLUTE-CONFIGURATION OF NYASICOSIDE - ITS OCCURRENCE IN CURCULIGO-RECURVATA [J].