Tea Consumption and Risk of Head and Neck Cancer

被引：14

作者：

Huang, Cheng-Chih ^{[1
]}

Lee, Wei-Ting ^{[1
]}

Tsai, Sen-Tien ^{[1
]}

Ou, Chun-Yen ^{[1
]}

Lo, Hung-i ^{[1
]}

Wong, Tung-Yiu ^{[2
]}

Fang, Sheen-Yie ^{[1
]}

Chen, Ken-Chung ^{[2
]}

Huang, Jehn-Shyun ^{[2
]}

Wu, Jiunn-Liang ^{[1
]}

Yen, Chia-Jui ^{[3
]}

Hsueh, Wei-Ting ^{[4
]}

Wu, Yuan-Hua ^{[4
]}

Yang, Ming-Wei ^{[4
]}

Lin, Forn-Chia ^{[4
]}

Chang, Jang-Yang ^{[3
,5
]}

Chang, Kwang-Yu ^{[3
,5
]}

Wu, Shang-Yin ^{[3
]}

Hsiao, Jenn-Ren ^{[1
]}

Lin, Chen-Lin ^{[6
]}

Wang, Yi-Hui ^{[5
]}

Weng, Ya-Ling ^{[5
]}

Yang, Han-Chien ^{[5
]}

Chang, Jeffrey S. ^{[5
]}

机构：

[1] Natl Cheng Kung Univ, Coll Med, Natl Cheng Kung Univ Hosp, Dept Otolaryngol, Tainan 70101, Taiwan

[2] Natl Cheng Kung Univ, Coll Med, Natl Cheng Kung Univ Hosp, Dept Stomatol, Tainan 70101, Taiwan

[3] Natl Cheng Kung Univ, Coll Med, Natl Cheng Kung Univ Hosp, Dept Internal Med,Div Hematol Oncol, Tainan 70101, Taiwan

[4] Natl Cheng Kung Univ, Coll Med, Natl Cheng Kung Univ Hosp, Dept Radiat Oncol, Tainan 70101, Taiwan

[5] Natl Hlth Res Inst, Natl Inst Canc Res, Tainan, Taiwan

[6] Natl Cheng Kung Univ, Coll Med, Natl Cheng Kung Univ Hosp, Dept Nursing, Tainan 70101, Taiwan

来源：

PLOS ONE | 2014年 / 9卷 / 05期

关键词：

UPPER-AERODIGESTIVE TRACT; ORAL-CANCER; ESOPHAGEAL CANCER; COFFEE; ALCOHOL; CAVITY; POLYPHENOLS; SMOKING; TOBACCO; LESIONS;

D O I：

10.1371/journal.pone.0096507

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

070301 [无机化学]; 070403 [天体物理学]; 070507 [自然资源与国土空间规划学]; 090105 [作物生产系统与生态工程];

摘要：

Background: The current study evaluated the association between tea consumption and head and neck cancer (HNC) in Taiwan, where tea is a major agricultural product and a popular beverage. Methods: Interviews regarding tea consumption (frequency, duration, and types) were conducted with 396 HNC cases and 413 controls. Unconditional logistic regression was performed to estimate the odds ratio (OR) and 95% confidence interval (CI) of HNC risk associated with tea drinking, adjusted for sex, age, education, cigarette smoking, betel quid chewing, and alcohol drinking. Results: A reduced HNC risk associated with tea drinking (OR for every cup per day = 0.96, 95% CI: 0.93-0.99; OR for >= 5 cups per day = 0.60, 95% CI: 0.39-0.94) was observed. The association was especially significant for pharyngeal cancer (OR for every cup per day = 0.93, 95% CI: 0.88-0.98; OR for >= 5 cups per day = 0.32, 95% CI: 0.16-0.66). A significant inverse association between HNC and tea consumption was observed particularly for green tea. Conclusions: This study suggests that tea drinking may reduce the risk of HNC. The anticancer property of tea, if proven, may offer a natural chemopreventive measure to reduce the occurrence of HNC.

引用

页数：9

共 36 条

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