Herbal preparations for the menopause: Beyond isoflavones and black cohosh

被引:47
作者
Depypere, Herman T. [1 ]
Comhaire, Frank H. [2 ]
机构
[1] Univ Hosp Ghent, Dept Obstet & Gynecol, Menopause Clin, B-9000 Ghent, Belgium
[2] Univ Hosp Ghent, Dept Endocrinol & Metab Dis, B-9000 Ghent, Belgium
关键词
Menopause; Treatment; Herbal medicine; Nutraceutical; PLACEBO-CONTROLLED-TRIAL; STANDARDIZED HOP EXTRACT; DOUBLE-BLIND; POSTMENOPAUSAL WOMEN; CLIMACTERIC SYNDROME; BREAST-CANCER; CROSS-OVER; SYMPTOMS; INDOLE-3-CARBINOL; SUPPLEMENTATION;
D O I
10.1016/j.maturitas.2013.11.001
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
030301 [社会学]; 100201 [内科学];
摘要
Complementary and alternative medicines (CAM) such as isoflavones and black cohosh are commonly used to deal with menopausal symptoms, but benefit a limited proportion of women. The aim of this minireview is to summarize the evidence of the efficacy and safety of other herbal preparations. Randomized controlled trials (RCTs) find that the extracts of Mediterranean pine bark (Pycnogenol (R)), linseed, and Lepididium meyenii (Maca) reduce vasomotor symptoms. The results of RCTs of the hop flavonoid 8-prenylnaringenin are conflicting. Animal and human studies suggest that Dioscorea villosa (Wild yam),and Broccoli may protect against osteoporosis and breast and gynecological cancers but further evidence is required. Linseed may protect against breast cancer but the results are conflicting. (C) 2013 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:191 / 194
页数:4
相关论文
共 26 条
[1]
Placebo-controlled trial of indole-3-carbinol in the treatment of CIN [J].
Bell, MC ;
Crowley-Nowick, P ;
Bradlow, HL ;
Sepkovic, DW ;
Schmidt-Grimminger, D ;
Howell, P ;
Mayeaux, EJ ;
Tucker, A ;
Turbat-Herrera, EA ;
Mathis, JM .
GYNECOLOGIC ONCOLOGY, 2000, 78 (02) :123-129
[2]
Disposition of hop prenylflavonoids in human breast tissue [J].
Bolca, Selin ;
Li, Jinghu ;
Nikolic, Dejan ;
Roche, Nathalie ;
Blondeel, Phillip ;
Possemiers, Sam ;
De Keukeleire, Denis ;
Bracke, Marc ;
Heyerick, Arne ;
van Breemen, Richard B. ;
Depypere, Herman .
MOLECULAR NUTRITION & FOOD RESEARCH, 2010, 54 :S284-S294
[3]
Alternative and complementary therapies for the menopause [J].
Borrelli, Francesca ;
Ernst, Edzard .
MATURITAS, 2010, 66 (04) :333-343
[4]
Brooks JD, 2004, AM J CLIN NUTR, V79, P318
[5]
Estimated enterolignans, lignan-rich foods, and fibre in relation to survival after postmenopausal breast cancer [J].
Buck, K. ;
Zaineddin, A. K. ;
Vrieling, A. ;
Heinz, J. ;
Linseisen, J. ;
Flesch-Janys, D. ;
Chang-Claude, J. .
BRITISH JOURNAL OF CANCER, 2011, 105 (08) :1151-1157
[6]
Osteoprotective Effect of Monascus-fermented Dioscorea in Ovariectomized Rat Model of Postmenopausal Osteoporosis [J].
Chiang, Shen-Shih ;
Chang, Shang-Ping ;
Pan, Tzu-Ming .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2011, 59 (17) :9150-9157
[7]
Evaluation of the Efficacy of Flaxseed Meal and Flaxseed Extract in Reducing Menopausal Symptoms [J].
Colli, Marcia Constantino ;
Bracht, Adelar ;
Soares, Andrea Assuncao ;
de Oliveira, Andrea Luisa ;
Boer, Cinthia Gandolfi ;
Marques de Souza, Cristina Giatti ;
Peralta, Rosane Marina .
JOURNAL OF MEDICINAL FOOD, 2012, 15 (09) :840-845
[8]
Effects of Pycnogenol on endothelial function in patients with stable coronary artery disease: a double-blind, randomized, placebo-controlled, cross-over study [J].
Enseleit, Frank ;
Sudano, Isabella ;
Periat, Daniel ;
Winnik, Stephan ;
Wolfrum, Mathias ;
Flammer, Andreas J. ;
Froehlich, Georg M. ;
Kaiser, Priska ;
Hirt, Astrid ;
Haile, Sarah R. ;
Krasniqi, Nazmi ;
Matter, Christian M. ;
Uhlenhut, Klaus ;
Hoegger, Petra ;
Neidhart, Michel ;
Luescher, Thomas F. ;
Ruschitzka, Frank ;
Noll, Georg .
EUROPEAN HEART JOURNAL, 2012, 33 (13) :1589-1597
[9]
A randomized, double-blind, placebo-controlled, cross-over pilot study on the use of a standardized hop extract to alleviate menopausal discomforts [J].
Erkkola, R. ;
Vervarcke, S. ;
Vansteelandt, S. ;
Rompotti, P. ;
De Keukeleire, D. ;
Heyerick, A. .
PHYTOMEDICINE, 2010, 17 (06) :389-396
[10]
Errichi S, 2011, Panminerva Med, V53, P65