Complementary and alternative medicines (CAM) such as isoflavones and black cohosh are commonly used to deal with menopausal symptoms, but benefit a limited proportion of women. The aim of this minireview is to summarize the evidence of the efficacy and safety of other herbal preparations. Randomized controlled trials (RCTs) find that the extracts of Mediterranean pine bark (Pycnogenol (R)), linseed, and Lepididium meyenii (Maca) reduce vasomotor symptoms. The results of RCTs of the hop flavonoid 8-prenylnaringenin are conflicting. Animal and human studies suggest that Dioscorea villosa (Wild yam),and Broccoli may protect against osteoporosis and breast and gynecological cancers but further evidence is required. Linseed may protect against breast cancer but the results are conflicting. (C) 2013 Elsevier Ireland Ltd. All rights reserved.
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German Canc Res Ctr, Div Canc Epidemiol, Unit Genet Epidemiol, Heidelberg, GermanyGerman Canc Res Ctr, Div Canc Epidemiol, Unit Genet Epidemiol, Heidelberg, Germany
Buck, K.
;
Zaineddin, A. K.
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German Canc Res Ctr, Div Canc Epidemiol, Unit Genet Epidemiol, Heidelberg, GermanyGerman Canc Res Ctr, Div Canc Epidemiol, Unit Genet Epidemiol, Heidelberg, Germany
Zaineddin, A. K.
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Vrieling, A.
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German Canc Res Ctr, Div Canc Epidemiol, Unit Genet Epidemiol, Heidelberg, GermanyGerman Canc Res Ctr, Div Canc Epidemiol, Unit Genet Epidemiol, Heidelberg, Germany
Vrieling, A.
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Heinz, J.
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UCCH, Clin Canc Registry, Dept Canc Epidemiol, D-20246 Hamburg, GermanyGerman Canc Res Ctr, Div Canc Epidemiol, Unit Genet Epidemiol, Heidelberg, Germany
Heinz, J.
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Linseisen, J.
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Helmholtz Ctr Munich, Inst Epidemiol, D-86746 Neuherberg, GermanyGerman Canc Res Ctr, Div Canc Epidemiol, Unit Genet Epidemiol, Heidelberg, Germany
Linseisen, J.
;
Flesch-Janys, D.
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UCCH, Clin Canc Registry, Dept Canc Epidemiol, D-20246 Hamburg, Germany
Univ Med Ctr Hamburg Eppendorf, Ctr Med Expt, Dept Med Biometry & Epidemiol, D-20246 Hamburg, GermanyGerman Canc Res Ctr, Div Canc Epidemiol, Unit Genet Epidemiol, Heidelberg, Germany
Flesch-Janys, D.
;
Chang-Claude, J.
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German Canc Res Ctr, Div Canc Epidemiol, Unit Genet Epidemiol, Heidelberg, GermanyGerman Canc Res Ctr, Div Canc Epidemiol, Unit Genet Epidemiol, Heidelberg, Germany
机构:
German Canc Res Ctr, Div Canc Epidemiol, Unit Genet Epidemiol, Heidelberg, GermanyGerman Canc Res Ctr, Div Canc Epidemiol, Unit Genet Epidemiol, Heidelberg, Germany
Buck, K.
;
Zaineddin, A. K.
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German Canc Res Ctr, Div Canc Epidemiol, Unit Genet Epidemiol, Heidelberg, GermanyGerman Canc Res Ctr, Div Canc Epidemiol, Unit Genet Epidemiol, Heidelberg, Germany
Zaineddin, A. K.
;
Vrieling, A.
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German Canc Res Ctr, Div Canc Epidemiol, Unit Genet Epidemiol, Heidelberg, GermanyGerman Canc Res Ctr, Div Canc Epidemiol, Unit Genet Epidemiol, Heidelberg, Germany
Vrieling, A.
;
Heinz, J.
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UCCH, Clin Canc Registry, Dept Canc Epidemiol, D-20246 Hamburg, GermanyGerman Canc Res Ctr, Div Canc Epidemiol, Unit Genet Epidemiol, Heidelberg, Germany
Heinz, J.
;
Linseisen, J.
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Helmholtz Ctr Munich, Inst Epidemiol, D-86746 Neuherberg, GermanyGerman Canc Res Ctr, Div Canc Epidemiol, Unit Genet Epidemiol, Heidelberg, Germany
Linseisen, J.
;
Flesch-Janys, D.
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UCCH, Clin Canc Registry, Dept Canc Epidemiol, D-20246 Hamburg, Germany
Univ Med Ctr Hamburg Eppendorf, Ctr Med Expt, Dept Med Biometry & Epidemiol, D-20246 Hamburg, GermanyGerman Canc Res Ctr, Div Canc Epidemiol, Unit Genet Epidemiol, Heidelberg, Germany
Flesch-Janys, D.
;
Chang-Claude, J.
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German Canc Res Ctr, Div Canc Epidemiol, Unit Genet Epidemiol, Heidelberg, GermanyGerman Canc Res Ctr, Div Canc Epidemiol, Unit Genet Epidemiol, Heidelberg, Germany