First outbreak of vancomycin-resistant enterococci in a tertiary hospital in Turkey

被引：32

作者：

Colak, D

Naas, T ^{[1
]}

Gunseren, F

Fortineau, N

Ogunc, D

Gultekin, M

Nordmann, P

机构：

[1] Akdeniz Univ Sch Med, Dept Infect Dis, Antalya, Turkey

[2] Akdeniz Univ Sch Med, Dept Clin Microbiol, Antalya, Turkey

[3] Assistance Publ Hop Paris, Hop Bicetre, Fac Med Paris Sud, Serv Bacteriol Virol, F-94275 Le Kremlin Bicetre, France

来源：

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | 2002年 / 50卷 / 03期

关键词：

Enterococcus faecium; VRE; outbreak;

D O I：

10.1093/jac/dkf134

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Twenty multidrug-resistant vancomycin-resistant Enterococcus faecium strains of the VanA phenotype were isolated over a 1 year period from five patients in the intensive care unit at the University Hospital of Antalya, Turkey. Molecular investigation showed that these strains belonged to five different pulsotypes and that the vanA gene was carried by a Tn1546-like transposon inserted onto a self-transferable plasmid of approximately 200 kb. One patient was infected by two different strains, suggesting horizontal gene transfer within that patient. This is the first documented outbreak of VRE in Turkey with concomitant spread of plasmid and strains.

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页码：397 / 401

页数：5

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