DNA architecture: from G to Z

被引：241

作者：

Phan, Anh Tuan ^{[1
]}

Kuryavyi, Vitaly ^{[1
]}

Patel, Dinshaw J. ^{[1
]}

机构：

[1] Mem Sloan Kettering Canc Ctr, Struct Biol Program, New York, NY 10021 USA

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 2006年 / 16卷 / 03期

关键词：

D O I：

10.1016/j.sbi.2006.05.011

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

G-quadruplexes and Z-DNA are two important non-B forms of DNA architecture. Results on novel structural elements, folding and unfolding kinetics, and interactions with small molecules and proteins have been reported recently for these forms. These results will enhance our understanding of the biology of these structures and provide a platform for drug design.

引用

页码：288 / 298

页数：11

共 69 条

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