Antiinflammatory effects of escins Ia, Ib, IIa, and IIb from horse chestnut, the seeds of Aesculus hippocastanum L.

被引：35

作者：

Matsuda, H

Li, YH

Murakami, T

Ninomiya, K

Araki, N

Yoshikawa, M

Yamahara, J

机构：

[1] KYOTO PHARMACEUT UNIV,YAMASHIMA KU,KYOTO 607,JAPAN

[2] RES INST PROD DEV,SAKYO KU,KYOTO 606,JAPAN

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1997年 / 7卷 / 13期

关键词：

D O I：

10.1016/S0960-894X(97)00275-8

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

We have investigated the effects of escins Ia, Ib, IIa, and IIb, isolated from horse chestnut, the seeds of Aesculus hippocastanum L. and desacylescins I and II obtained by alkaline hydrolysis of escins on acute inflammation in experimental animal models, and some structure-requirements of escins for the activity was obtained. (C) 1997 Elsevier Science Ltd.

引用

页码：1611 / 1616

页数：6

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