Nucleation mechanisms in protein folding

被引：464

作者：

Fersht, AR

机构：

[1] Cambridge Univ. Chemical Laboratory, Lensfield Road, CB2 1EW, Cambridge

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 1997年 / 7卷 / 01期

关键词：

D O I：

10.1016/S0959-440X(97)80002-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Experiment and theory are converging on the importance of nucleation mechanisms in protein folding. These mechanisms do not use classic nuclei, which are well formed elements of structure present in ground states, but they use diffuse, extended regions, which are observed in transition states.

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页码：3 / 9

页数：7

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