Enantioselective photoreduction of arylalkyl ketones via restricting the reaction to chirally modified zeolite cages

被引:17
作者
Shailaja, J [1 ]
Ponchot, KJ [1 ]
Ramamurthy, V [1 ]
机构
[1] Tulane Univ, Dept Chem, New Orleans, LA 70118 USA
关键词
D O I
10.1021/ol000018e
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
[GRAPHICS] Obtaining a high enantiomeric excess during a photoreaction within a zeolite is hampered by the statistical distribution of reactant and chiral inductor molecules within the cages of a zeolite. By restricting the photoreactions to only those cages that contain both the reactant and a chiral inductor, one should be able to avoid reactions that yield racemic products. This approach is illustrated with the photoreduction of an arylalkyl ketone by a chiral inductor with an amino group.
引用
收藏
页码:937 / 940
页数:4
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