Phase behavior of concentrated hydroxypropyl methylcellulose solution in the presence of mono and divalent salt

被引：23

作者：

Almeida, Nalinda ^{[1
]}

Rakesh, Leela ^{[1
,2
]}

Zhao, Jin ^{[3
]}

机构：

[1] Cent Michigan Univ, Mt Pleasant, MI 48859 USA

[2] Cent Michigan Univ, Dept Math, Ctr Appl Math & Polymer Fluid Dynam, Mt Pleasant, MI 48859 USA

[3] Dow Chem Co USA, Dow Pharma & Food Solut, Midland, MI 48674 USA

来源：

CARBOHYDRATE POLYMERS | 2014年 / 99卷

关键词：

Hydroxypropylmethylcellulose; Phase behavior; Mono and divalent salt; Gelation; Rheology; Differential scanning calorimetry; Viscoelasticity; AQUEOUS-SOLUTIONS; THERMOREVERSIBLE GELATION; CELLULOSE ETHERS; MATRIX TABLETS; HYDROXYPROPYLMETHYLCELLULOSE; WATER; HYDROGELS; GELS;

D O I：

10.1016/j.carbpol.2013.08.081

中图分类号：

O69 [应用化学];

学科分类号：

070301 [无机化学];

摘要：

Thermo reversible sol-gel transitions of hydroxypropylmethylcellulose (HPMC) are critical for many pharmaceutical, cosmetic, and food applications. This study examined the effects of salt (NaCl and CaCl2) on the viscoelastic properties of concentrated low molecular weight HPMC solutions and found that the gelation temperature decreased linearly as a function of salt concentrations, independent of valency of cations and the mole concentration of anions. Thermal analysis showed that the depression of melting temperature can be fitted for both NaCl and CaCl2 as a function of the total number of ions by a single linear curve, which was consistent with the melting point depression of pure water by NaCl and CaCl2, but with a higher linear slope. Published by Elsevier Ltd.

引用

页码：630 / 637

页数：8

共 23 条

[1]

Differential scanning calorimetry investigation of the effect of salts on aqueous solution properties of an amphiphilic block copolymer (Poloxamer) [J].