Placental transfer of ganciclovir in a woman with acquired immunodeficiency syndrome and cytomegalovirus disease

被引：23

作者：

Brady, RC ^{[1
]}

Schleiss, MR

Witte, DP

Siddiqi, TA

Frame, PT

机构：

[1] Cincinnati Childrens Hosp, Ctr Med, Dept Pediat, Cincinnati, OH 45229 USA

[2] Univ Cincinnati, Med Ctr, Dept Internal Med, Cincinnati, OH 45267 USA

[3] Univ Cincinnati, Med Ctr, Dept Obstet & Gynecol, Cincinnati, OH 45267 USA

来源：

PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2002年 / 21卷 / 08期

关键词：

congenital cytomegalovirus infection; neonate; acquired immunodeficiency syndrome; ganciclovir;

D O I：

10.1097/00006454-200208000-00023

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A pregnant woman with AIDS developed cytomegalovirus (CATV) retinitis and pneumonitis, requiring intravenous ganciclovir. At 34 weeks gestation the woman delivered a 1.4-kg girl. Examination of the placenta revealed transplacental passage of CMV. Low concentrations of ganciclovir were detected in the neonate's plasma. The neonate had mild anemia but no other signs of congenital CMV infection.

引用

页码：796 / 797

页数：2

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