Cardioprotective Properties of the Platelet P2Y12 Receptor Inhibitor, Cangrelor: Protective in Diabetics and Reliant Upon the Presence of Blood

被引：33

作者：

Bell, R. M. ^{[1
]}

Sivaraman, V. ^{[1
]}

Kunuthur, S. P. ^{[1
]}

Cohen, M. V. ^{[2
]}

Downey, J. M. ^{[2
]}

Yellon, D. M. ^{[1
]}

机构：

[1] UCL, Inst Cardiovasc Sci, Hatter Cardiovasc Inst, London WC1E 6HX, England

[2] Univ S Alabama, Coll Med, Dept Physiol & Cell Biol & Med, Mobile, AL 36688 USA

来源：

CARDIOVASCULAR DRUGS AND THERAPY | 2015年 / 29卷 / 05期

基金：

英国医学研究理事会;

关键词：

Cangrelor; P2Y12; inhibitor; Cardioprotection; Ischaemia; Reperfusion injury; Anti-platelet; HEARTS;

D O I：

10.1007/s10557-015-6609-2

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

[No abstract available]

引用

页码：415 / 418

页数：4

共 8 条

[1]

Pharmacology of the New P2Y12 Receptor Inhibitors: Insights on Pharmacokinetic and Pharmacodynamic Properties [J].

Ferri, Nicola ;

Corsini, Alberto ;

Bellosta, Stefano .

DRUGS, 2013, 73 (15) :1681-1709

[2]

PRODUCTION OF SPONTANEOUS DIABETIC RATS BY REPETITION OF SELECTIVE BREEDING [J].

GOTO, Y ;

KAKIZAKI, M ;

MASAKI, N .

TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE, 1976, 119 (01) :85-90

[3]

The mitochondrial permeability transition pore as a target for preconditioning and postconditioning [J].

Hausenloy, Derek J. ;

Ong, Sang-Bing ;

Yellon, Derek M. .

BASIC RESEARCH IN CARDIOLOGY, 2009, 104 (02) :189-202

[4]

Comparison of Prasugrel and Ticagrelor Loading Doses in ST-Segment Elevation Myocardial Infarction Patients RAPID (Rapid Activity of Platelet Inhibitor Drugs) Primary PCI Study [J].

Parodi, Guido ;

Valenti, Renato ;

Bellandi, Benedetta ;

Migliorini, Angela ;

Marcucci, Rossella ;

Comito, Vincenzo ;

Carrabba, Nazario ;

Santini, Alberto ;

Gensini, Gian Franco ;

Abbate, Rosanna ;

Antoniucci, David .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2013, 61 (15) :1601-1606

[5]

Cardioprotection in the aging, diabetic heart: the loss of protective Akt signalling [J].

Whittington, Hannah J. ;

Harding, Idris ;

Stephenson, Clemency I. M. ;

Bell, Robert ;

Hausenloy, Derek J. ;

Mocanu, Mihaela M. ;

Yellon, Derek M. .

CARDIOVASCULAR RESEARCH, 2013, 99 (04) :694-704

[6]

Triple Therapy Greatly Increases Myocardial Salvage During Ischemia/Reperfusion in the in situ Rat Heart [J].

Yang, Xi-Ming ;

Cui, Lin ;

Alhammouri, Ahmad ;

Downey, James M. ;

Cohen, Michael V. .

CARDIOVASCULAR DRUGS AND THERAPY, 2013, 27 (05) :403-412

[7]

Platelet P2Y12 Blockers Confer Direct Postconditioning-Like Protection in Reperfused Rabbit Hearts [J].

Yang, Xi-Ming ;

Liu, Yanping ;

Cui, Lin ;

Yang, Xiulan ;

Liu, Yongge ;

Tandon, Narendra ;

Kambayashi, Junichi ;

Downey, James M. ;

Cohen, Michael V. .

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS, 2013, 18 (03) :251-262

[8]

Two Classes of Anti-Platelet Drugs Reduce Anatomical Infarct Size in Monkey Hearts [J].

Yang, Xi-Ming ;

Liu, Yanping ;

Cui, Lin ;

Yang, Xiulan ;

Liu, Yongge ;

Tandon, Narendra ;

Kambayashi, Junichi ;

Downey, James M. ;

Cohen, Michael V. .

CARDIOVASCULAR DRUGS AND THERAPY, 2013, 27 (02) :109-115

← 1 →