Bleb reduction and bleb repair after trabeculectomy

Objective: To describe methods and outcomes for repair of bleb-related complications of trabeculectomy surgery. Design: Retrospective, consecutive, noncomparative case series. Participants: Thirty-one persons having bleb revision by two surgeons at the Wilmer Institute from 1994 to the present. Intervention: One of two types of revision surgery was performed: bleb reduction to decrease symptoms from large blebs or bleb repair to improve hypotony, using conjunctival rotation flap or free conjunctival autograft. Main Outcome Measures: Visual acuity, intraocular pressure (IOP), reported symptoms, complications, and number of glaucoma medications at the final visit. Results: The mean time from trabeculectomy to bleb revision was 4.4 years. Bleb reduction was performed because of symptomatic, high blebs in 11 eyes of 11 persons. Bleb repair was performed to end bleb leakage in 13 eyes of 13 persons and to increase IOP in 8 eyes of 7 persons with hypotony, Median visual acuity improved from 20/50 before revision to 20/30 at most recent follow-up, Mean IOP increased after treatment from 7.7 +/- 4.9 to 12.4 +/- 4.0 mmHg (P < 0.001). Symptoms that caused the revision surgery were eliminated in all cases. None of these eyes has lost IOP control, none has required repeat trabeculectomy, and only 2 of the 32 (6%) require topical glaucoma medication. More than one revision procedure was required in 8 of 32 (25%) eyes. Conclusions: Surgical bleb revisions for complications after trabeculectomy surgery are safe and effective. Bleb reduction for large, symptomatic blebs or bleb repair for leaking blebs and hypotony did not lead to loss of IOP control. (C) 2000 by the American Academy of Ophthalmology.