Effectiveness of clopidogrel versus aspirin in preventing acute myocardial infarction in patients with symptomatic atherothrombosis (CAPRIE trial)

被引：67

作者：

Cannon, CP

机构：

[1] Brigham & Womens Hosp, Div Cardiovasc, Dept Med, Boston, MA 02115 USA

[2] Harvard Univ, Sch Med, Boston, MA USA

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 2002年 / 90卷 / 07期

关键词：

D O I：

10.1016/S0002-9149(02)02606-1

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This analysis of 19,185 patients in the Clopidogrel versus Aspirin in Patients at Risk of Ischemic Events trial demonstrated that acute myocardial infarction can be predicted using baseline characteristics across a wide range of risk, and that clopidogrel significantly reduced this relative risk by approximately 19% compared with aspirin. Contrary to our hypothesis, and in contrast to the effects of intravenous glycoprotein IIb/IIIa inhibitors, this reduction was present in both high- and low-risk patients.

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页码：760 / +

页数：4

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