An update on pharmacologic management of chronic obstructive pulmonary disease

被引:7
作者
Patel, Hetal J. [1 ]
机构
[1] Univ Texas Southwestern, Div Pulm & Crit Care Med, 5323 Harry Hines Blvd,MC 8558, Dallas, TX 75390 USA
关键词
chronic obstructive pulmonary disease; long-acting; -agonists; long-acting muscarinic antagonists; FIXED-DOSE COMBINATION; ACLIDINIUM BROMIDE/FORMOTEROL FUMARATE; COPD PATIENTS; GOLD; 2-4; EFFICACY; SAFETY; TIOTROPIUM; PLACEBO; OLODATEROL; UMECLIDINIUM;
D O I
10.1097/MCP.0000000000000240
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
100201 [内科学];
摘要
Purpose of reviewChronic obstructive pulmonary disease (COPD) is a widespread disease process with important clinical and economic implications. This review will summarize new pharmacotherapy for the treatment of COPD.Recent findingsSeveral recent clinical trials have led to the approval of new inhaler therapies for COPD. Many of these are specifically targeting combination long-acting -agonists and long-acting muscarinic antagonists for late stage COPD.SummarySeveral new bronchodilators are available on the market, especially in combination form. The new drug combinations have positive data though clinical relevance, and comparisons to available and well established therapies are still needed. Specifically, translating improved forced expiratory volume into meaningful clinical outcomes remains challenging.
引用
收藏
页码:119 / 124
页数:6
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