The myelinated axon is dependent on the myelinating cell for support and maintenance: Molecules involved

被引:54
作者
Edgar, JM
Garbern, J
机构
[1] Univ Glasgow, Dept Vet Clin Sci, Appl Neurobiol Grp, Inst Comparat Med, Glasgow G61 1QH, Lanark, Scotland
[2] Wayne State Univ, Dept Neurol, Detroit, MI USA
[3] Wayne State Univ, Ctr Mol Med & Genet, Detroit, MI USA
关键词
myelin; axon; proteolipid protein; 2; 3 '-cyclic nucleotide 3 '-phosphodiesterase;
D O I
10.1002/jnr.20063
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The myelin-forming cells, oligodendrocytes and Schwann cells, extend processes that spirally wrap axons and provide the insulation that allows rapid saltatory conduction. Recent data suggest a further role for the myelin-forming cells in axonal support and maintenance. This Mini-Review summarises some of the data that support this view and highlights the molecules involved. (C) 2004 Wiley-Liss, Inc.
引用
收藏
页码:593 / 598
页数:6
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