Monodisperse hydrophilic polymer microspheres having carboxylic acid groups prepared by distillation precipitation polymerization

被引：159

作者：

Bai, Feng ^{[1
]}

Yang, Xinlin ^{[1
]}

Li, Rui ^{[1
]}

Huang, Bo ^{[1
]}

Huang, Wenqiang ^{[1
]}

机构：

[1] Nankai Univ, Inst Polymer Chem, Key Lab Funct Polymer Mat, Minist Educ, Tianjin 300071, Peoples R China

来源：

POLYMER | 2006年 / 47卷 / 16期

关键词：

distillation precipitation polymerization; hydrophilic polymer microspheres; formation mechanism;

D O I：

10.1016/j.polymer.2006.06.014

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Monodisperse hydrophilic polymer microspheres having carboxyl acid group with spherical shape in the range of 160 nm and 1.52 mu m were prepared by distillation copolymerizations of (meth)acrylic acid with either ethyleneglycol dimethacrylate (EGDMA) or divinylbenzene (DVB) as crosslinker. Polymerization was carried out with 2,2'-azobisisobutyronitrile (AIBN) as initiator in neat acetonitrile without stirring. The polymer microspheres were formed and precipitated out from the reaction medium during the distillation of the solvent from the reaction system through an entropic precipitation polymerization manner. The effects of the crosslinker degree on the morphology and the loading capacity of the carboxylic acid group of the resultant polymer microspheres were investigated. The growth procedures of poly(DVB-co-AA) microspheres were traced by SEM characterization. The steric stabilization through the pendent chains and surface gel and the electrostatic repulsion from the carboxyl acid groups contribute to the formation of monodisperse polymer microspheres. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：5775 / 5784

页数：10

共 38 条

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