Obsessive-compulsive disorder

被引:281
作者
Stein, DJ [1 ]
机构
[1] Univ Stellenbosch, Dept Psychiat, Cape Town, South Africa
[2] Univ Florida, Gainesville, FL USA
关键词
D O I
10.1016/S0140-6736(02)09620-4
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Obsessive-compulsive disorder is a frequent, chronic, costly, and disabling disorder that presents in several medical settings, but is under-recognised and undertreated. For many years, obsessive-compulsive neurosis was seen as a disorder that provided an important window on the workings of the unconscious mind. Today, obsessive-compulsive disorder is viewed as a good example of a neuropsychiatric disorder, mediated by pathology in specific neuronal circuits, and responsive to specific pharmacotherapeutic and psychotherapeutic interventions. In the future we can expect more precise delineation of the origins of this disorder, with integration of data from neuroanatomical, neurochemical, neuroethological, neurogenetic, and neuroimmunological research.
引用
收藏
页码:397 / 405
页数:9
相关论文
共 123 条
[1]   Effectiveness of psychological and pharmacological treatments for obsessive-compulsive disorder: A quantitative review [J].
Abramowitz, JS .
JOURNAL OF CONSULTING AND CLINICAL PSYCHOLOGY, 1997, 65 (01) :44-52
[2]   Side effects as predictors of drug response in obsessive-compulsive disorder [J].
Ackerman, DL ;
Greenland, S ;
Bystritsky, A .
JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY, 1999, 19 (05) :459-465
[3]   Right prefrontal repetitive transcranial magnetic stimulation in obsessive-compulsive disorder:: A double-blind, placebo-controlled study [J].
Alonso, P ;
Pujol, J ;
Cardoner, N ;
Benlloch, L ;
Deus, J ;
Menchón, JM ;
Capdevila, A ;
Vallejo, J .
AMERICAN JOURNAL OF PSYCHIATRY, 2001, 158 (07) :1143-1145
[4]  
*AM AC CHILD AD PS, 1998, J AM ACAD CHILD PSY, V37, P27
[5]  
AMES D, 1994, J NEUROPSYCH CLIN N, V6, P100
[6]  
[Anonymous], 1997, Behav Res Ther, V35, P667
[7]  
[Anonymous], 1996, GLOBAL BURDEN DIS IN
[8]  
[Anonymous], DIAGN STAT MANN MENT
[9]  
[Anonymous], 1993, OBSESSIVE COMPULSIVE
[10]  
[Anonymous], 2001, ARCH WOMEN MENT HLTH, DOI DOI 10.1007/S007370170004