The first total synthesis of annonacin, the most typical monotetrahydrofuran annonaceous acetogenins

被引：23

作者：

Hu, TS

Wu, YL

Wu, YK

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Bioorgan & Nat Prod Chem, Shanghai 200032, Peoples R China

[2] Chinese Acad Sci, Shanghai Inst Organ Chem, Shanghai Hong Kong Joint Lab Chem Synthesis, Shanghai 200032, Peoples R China

来源：

ORGANIC LETTERS | 2000年 / 2卷 / 07期

关键词：

D O I：

10.1021/ol005504g

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] The first total synthesis of annonacin (1) was achieved by a highly convergent synthetic strategy. All the stereogenic centers were derived from three natural hydroxy acids respectively, except that those at C19 and C20 were produced from a Sharpless AD reaction.

引用

页码：887 / 889

页数：3

共 18 条

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