Highly diastereoselective synthesis of densely functionalized cyclopentanoids by intramolecular azomethine imine cycloadditions in sugar templates

被引：25

作者：

Gallos, JK

Koumbis, AE

Apostolakis, NE

机构：

[1] Department of Chemistry, Aristotle University of Thessaloniki

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1997年 / 17期

关键词：

D O I：

10.1039/a704207h

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Conversion of a sugar to a delta,epsilon -unsaturated aldehyde, and subsequent condensation of the aldehyde moiety with BnNHNHCO2Et, yields the respective azomethine imine intermediate dipole which adds intramolecularly to the existing double bond, thus generating a bicyclic adduct with high diastereoselectivity.

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页码：2457 / 2459

页数：3

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