Concentration of selenium in the whole blood and the thyroid tissue of patients with various thyroid diseases

被引：124

作者：

Kucharzewski, A

Braziewicz, J

Majewska, U

Gózdz, S

机构：

[1] L Warynski Silesian Med Acad, Dept Gen Surg, PL-41902 Bytom, Poland

[2] Holycross Canc Ctr, PL-25734 Kielce, Poland

[3] Jan Kochanowski Univ Humanities & Sci, Inst Phys, PL-25406 Kielce, Poland

来源：

BIOLOGICAL TRACE ELEMENT RESEARCH | 2002年 / 88卷 / 01期

关键词：

trace element; selenium; thyroid disease;

D O I：

10.1385/BTER:88:1:25

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

We investigated the possible differences between the concentrations of selenium in the whole blood and thyroid tissue of patients with thyroid disease. The study comprises 41 women with nodular goiter, 19 women and 2 men with thyroid cancer, 18 women with Graves' disease, and 7 women with thyroiditis. The concentration of selenium was determined by the TRXRF method. The lowest mean selenium level was achieved in the whole blood of women with Graves' disease and the highest in the whole blood of healthy people. In the thyroid cancer tissue, we found the lowest concentration of selenium and the highest in the thyroid gland of women with nodular goiter and Graves' disease. The low selenium levles in the thyroid tissue may increase thyroid cancer risk.

引用

页码：25 / 30

页数：6

共 17 条

[1]

SELENIUM CONCENTRATIONS IN THE HUMAN THYROID-GLAND [J].