Mechanisms of disease: erythropoietin - an old hormone with a new mission?

被引：26

作者：

Fliser, Danilo

Bahlmann, Ferdinand H.

deGroot, Kirsten

Haller, Hermann

机构：

[1] Hannover Med Sch, Dept Internal Med, Div Nephrol, D-30625 Hannover, Germany

[2] Klinikum Offenbach, Offenbach, Germany

来源：

NATURE CLINICAL PRACTICE CARDIOVASCULAR MEDICINE | 2006年 / 3卷 / 10期

关键词：

Akt activation; apoptosis; cardiovascular protection; erythropoietin; renoprotection;

D O I：

10.1038/ncpcardio0609

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The major physiological function of erythropoietin is the induction of erythropoiesis. A growing body of evidence indicates, however, that this hormone has tissue-protective effects and prevents tissue damage during ischemia and inflammation. This review article summarizes the present knowledge on the cardiovascular and renal protective effects of erythropoietin and discusses the possible underlying mechanisms.

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收藏

页码：563 / 572

页数：10

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