Analysis of survival data with cross-effects of survival functions

被引：23

作者：

Bagdonavicius, V

Hafdi, MA

Nikulin, M

机构：

[1] Vilnius State Univ, Dept Math Stat, Vilnius, Lithuania

[2] Mohammed V Univ Rabat, Rabat, Morocco

[3] Victor Segalen Univ, IFR 99 Sante Publ, Bordeaux, France

[4] VA Steklov Math Inst, RAN, St Petersburg 191011, Russia

来源：

BIOSTATISTICS | 2004年 / 5卷 / 03期

关键词：

CE model; chemotherapy; Chi-squared type test; cross-effects; gastric cancer data; gastrointestinal tumor; GPH model; Hougaard-Aalen model; Hsieh model; PH model; radiotherapy; semiparametric likelihood; survival;

D O I：

10.1093/biostatistics/kxg045

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

We present a model and semiparametric estimation procedures for analyzis of survival data with cross-effects (CE) of survival functions. Finite sample properties of the estimators are analyzed by simulation. A goodness-of-fit test for the proportional hazards model against the CE model is proposed. The well known data concerning effects of chemotherapy and radiotherapy on the survival times of gastric cancer patients is analyzed as an example.

引用

页码：415 / 425

页数：11

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