Cell biology -: Brief encounters bolster contacts

被引：41

作者：

Blundell, Tom L.

Fernandez-Recio, Juan

机构：

[1] Univ Cambridge, Dept Biochem, Cambridge CB2 1GA, England

[2] Inst Biomed Res, Barcelona 08028, Spain

来源：

NATURE | 2006年 / 444卷 / 7117期

关键词：

D O I：

10.1038/nature05306

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Molecules often work together in complexes to carry out their functions in the cell. But how do they get together in such a dynamic environment? A structural study follows proteins as they meet their partners.

引用

页码：279 / 280

页数：2

共 14 条

[1] Protein docking along smooth association pathways [J].

Camacho, CJ ;

Vajda, S .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (19) :10636-10641

[2] Close encounters of the transient kind: Protein interactions in the photosynthetic redox chain investigated by NMR spectroscopy [J].

Crowley, PB ;

Ubbink, M .

ACCOUNTS OF CHEMICAL RESEARCH, 2003, 36 (10) :723-730

[3] Conformer generation under restraints [J].

de Bakker, PI ;

Furnham, N ;

Blundell, TL ;

DePristo, MA .

CURRENT OPINION IN STRUCTURAL BIOLOGY, 2006, 16 (02) :160-165

[4] Identification of protein-protein interaction sites from docking energy landscapes [J].

Fernández-Recio, J ;

Totrov, M ;

Abagyan, R .

JOURNAL OF MOLECULAR BIOLOGY, 2004, 335 (03) :843-865

[5] Is one solution good enough? [J].

Furnham, N ;

Blundell, TL ;

DePristo, MA ;

Terwilliger, TC .

NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2006, 13 (03) :184-185

[6] Biomolecular diffusional association [J].

Gabdoulline, RR ;

Wade, RC .

CURRENT OPINION IN STRUCTURAL BIOLOGY, 2002, 12 (02) :204-213

[7] Functional organization of the yeast proteome by systematic analysis of protein complexes [J].

Gavin, AC ;

Bösche, M ;

Krause, R ;

Grandi, P ;

Marzioch, M ;

Bauer, A ;

Schultz, J ;

Rick, JM ;

Michon, AM ;

Cruciat, CM ;

Remor, M ;

Höfert, C ;

Schelder, M ;

Brajenovic, M ;

Ruffner, H ;

Merino, A ;

Klein, K ;

Hudak, M ;

Dickson, D ;

Rudi, T ;

Gnau, V ;

Bauch, A ;

Bastuck, S ;

Huhse, B ;

Leutwein, C ;

Heurtier, MA ;

Copley, RR ;

Edelmann, A ;

Querfurth, E ;

Rybin, V ;

Drewes, G ;

Raida, M ;

Bouwmeester, T ;

Bork, P ;

Seraphin, B ;

Kuster, B ;

Neubauer, G ;

Superti-Furga, G .

NATURE, 2002, 415 (6868) :141-147

[8] Protein-protein docking predictions for the CAPRI experiment [J].

Gray, JJ ;

Moughon, SE ;

Kortemme, T ;

Schueler-Furman, O ;

Misura, KMS ;

Morozov, AV ;

Baker, D .

PROTEINS-STRUCTURE FUNCTION AND GENETICS, 2003, 52 (01) :118-122

[9] The structural biology of growth factor receptor activation [J].

Harmer, NJ ;

Chirgadze, D ;

Kim, KH ;

Pellegrini, L ;

Blundell, TL .

BIOPHYSICAL CHEMISTRY, 2003, 100 (1-3) :545-553

[10] Detecting transient intermediates in macromolecular binding by paramagnetic NMR [J].

Iwahara, J ;

Clore, GM .

NATURE, 2006, 440 (7088) :1227-1230

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