P-glycoprotein expression by peripheral blood mononuclear cells from human immunodeficiency virus-infected patients is independent from response to highly active antiretroviral therapy

被引：6

作者：

Agrati, C ^{[1
]}

Poccia, F

Topino, S

Narciso, P

Selva, C

Pucillo, LP

D'Offizi, G

Antonelli, G

Bellomi, F

Turriziani, O

Bambacioni, F

机构：

[1] IRCCS, Natl Inst Infect Dis L Spallanzani, Rome, Italy

[2] Univ Roma La Sapienza, Dept Expt Med & Pathol, Virol Sect, Rome, Italy

来源：

CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY | 2003年 / 10卷 / 01期

关键词：

D O I：

10.1128/CDLI.10.1.191-192.2003

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

引用

页码：191 / 192

页数：2

共 16 条

[1] Abnormal expression of a 170-kilodalton P-glycoprotein encoded by MDR1 gene, a metabolically active efflux pump, in CD4(+) and CD8(+) T cells from patients with human immunodeficiency virus type 1 infection [J].

Andreana, A ;

Aggarwal, S ;

Gollapudi, S ;

Wien, D ;

Tsuruo, T ;

Gupta, S .

AIDS RESEARCH AND HUMAN RETROVIRUSES, 1996, 12 (15) :1457-1462

[2] RESISTANCE OF HIV-1 TO AZT MIGHT ALSO INVOLVE THE CELLULAR EXPRESSION OF MULTIDRUG RESISTANCE P-GLYCOPROTEIN [J].

ANTONELLI, G ;

TURRIZIANI, O ;

CIANFRIGLIA, M ;

RIVA, E ;

DONG, G ;

FATTOROSSI, A ;

DIANZANI, F .

AIDS RESEARCH AND HUMAN RETROVIRUSES, 1992, 8 (10) :1839-1844

[3] MULTIDRUG RESISTANCE ACTIVITY IN HUMAN-LYMPHOCYTES [J].

COON, JS ;

WANG, YZ ;

BINES, SD ;

MARKHAM, PN ;

CHONG, ASF ;

GEBEL, HM .

HUMAN IMMUNOLOGY, 1991, 32 (02) :134-140

[4]

DRACH D, 1992, BLOOD, V80, P2729

[5] Pharmacologic considerations for therapeutic success with antiretroviral agents [J].

Fletcher, CV .

ANNALS OF PHARMACOTHERAPY, 1999, 33 (09) :989-995

[6] PREFERENTIAL EXPRESSION AND ACTIVITY OF MULTIDRUG RESISTANCE GENE-1 PRODUCT (P-GLYCOPROTEIN), A FUNCTIONALLY ACTIVE EFFLUX PUMP, IN HUMAN CD8+ T-CELLS - A ROLE IN CYTOTOXIC EFFECTOR FUNCTION [J].

GUPTA, S ;

KIM, CH ;

TSURUO, T ;

GOLLAPUDI, S .

JOURNAL OF CLINICAL IMMUNOLOGY, 1992, 12 (06) :451-458

[7] The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors [J].

Kim, RB ;

Fromm, MF ;

Wandel, C ;

Leake, B ;

Wood, AJJ ;

Roden, DM ;

Wilkinson, GR .

JOURNAL OF CLINICAL INVESTIGATION, 1998, 101 (02) :289-294

[8] TRANSMEMBRANE P-GLYCOPROTEIN (P-GP/P-170) IN HIV-INFECTION - ANALYSIS OF LYMPHOCYTE SURFACE EXPRESSION AND DRUG-UNRELATED FUNCTION [J].

LUCIA, MB ;

CAUDA, R ;

LANDAY, AL ;

MALORNI, W ;

DONELLI, G .

AIDS RESEARCH AND HUMAN RETROVIRUSES, 1995, 11 (08) :893-901

[9] Expression of P-glycoprotein and multidrug resistance-associated protein in healthy volunteers and HIV-infected patients [J].

Meaden, ER ;

Hoggard, PG ;

Maher, B ;

Khoo, SH ;

Back, DJ .

AIDS RESEARCH AND HUMAN RETROVIRUSES, 2001, 17 (14) :1329-1332

[10] Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection [J].

Palella, FJ ;

Delaney, KM ;

Moorman, AC ;

Loveless, MO ;

Fuhrer, J ;

Satten, GA ;

Aschman, DJ ;

Holmberg, SD .

NEW ENGLAND JOURNAL OF MEDICINE, 1998, 338 (13) :853-860

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