Looking for new paradigms towards a biological-mathematical theory of complex multicellular systems

被引:55
作者
Bellomo, Nicola
Forni, Guido
机构
[1] Politecn Torino, Dipartimento Matemat, I-10129 Turin, Italy
[2] Univ Turin, Osped San Luigi Gonzaga, Dept Clin & Biol Sci, I-10043 Orbassano, Italy
关键词
kinetic theory; statistical mechanics; complex systems in biology; nonlinearity;
D O I
10.1142/S0218202506001443
中图分类号
O29 [应用数学];
学科分类号
070104 [应用数学];
摘要
This paper deals with the development of new paradigms based on the methods of the mathematical kinetic theory for active particles to model the dynamics of large systems of interacting cells. Interactions are ruled, not only by laws of classical mechanics, but also by a few biological functions which are able to modify the above laws. The paper technically shows, also by reasoning oil specific examples, how the theory can be applied to model large complex systems in biology. The last part of the paper deals with a critical analysis and with the indication of research perspectives concerning the challenging target of developing a biological-mathematical theory for the living matter.
引用
收藏
页码:1001 / 1029
页数:29
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