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The role of C-reactive protein in mood disorders

被引：47
作者：
De Berardis, D.
Campanella, D.
Gambi, F.
La Rovere, R.
Carano, A.
Conti, C. M.
Silvestrini, C.
Serroni, N.
Piersanti, D.
Di Giuseppe, B.
Moschetta, F. S.
Cotellessa, C.
Fulcheri, M.
Salerno, R. M.
Ferro, F. M.
机构：
[1] Univ G DAnnunzio, Inst Psychiat, Dept Oncol & Neurosci, Scuole Specializzaz, I-66013 Chieti, Italy
[2] Univ G dAnnunzio, Dept Psychol, Chieti, Italy
[3] Dept Mental Hlth, Teramo, Italy
来源：
INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY | 2006年 / 19卷 / 04期
关键词：
C-reactive protein; depressive symptoms; bipolar disorder; coronary heart disease;
D O I：
10.1177/039463200601900402
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Recently, a possible relationship between C-Reactive Protein (CRP), a marker of underlying low-grade inflammation, and mood disorders has been proposed by some researchers. The aim of this review is to elucidate the current facts and views about CRP in mood disorders such as Depressive and Bipolar Disorders. Several studies have examined the relationship between affective disorders and CRP, but the majority of the studies in literature have been limited by retrospective, case-controlled study design, and very few studies have examined the relationship between depression and CRP in large study samples. In conclusion, the role of CRP in mood disorders is, to date, intriguing but somewhat unclear. Further prospective studies are needed to introduce the CRP in clinical settings as a marker of affective states and suicidability.
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收藏
页码：721 / 725
页数：5
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