To be or not to be a pro-T?

被引:24
作者
Di Santo, JP
Radtke, F
Rodewald, HR
机构
[1] Inst Pasteur, Unite Cytokines & Dev Lymphoide, F-75724 Paris, France
[2] Univ Lausanne, Ludwig Inst Canc Res, Lausanne Branch, CH-1066 Epalinges, Switzerland
[3] Univ Ulm, Immunol Klin, D-89081 Ulm, Germany
关键词
D O I
10.1016/S0952-7915(99)00066-7
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Recent studies have begun to unravel some of the molecular pathways that appear to control the processes of T cell determination in the earliest thymocyte precursors. In addition, the analyses of mouse mutants with an entirely alymphoid thymus have shed light on the developmental relationship of pro-T cells and thymic dendritic cells, revealing that development of thymocytes and thymic dendritic cells can be dissociated.
引用
收藏
页码:159 / 165
页数:7
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