Laparoscopic spleen-preserving distal pancreatectomy as treatment for nesidioblastosis after gastric bypass surgery

被引：47

作者：

Alvarez, Glauco C. ^{[1
]}

Faria, Everton N. ^{[1
]}

Beck, Maristela ^{[1
]}

Girardon, Dener T. ^{[1
]}

Machado, Ana Cristina ^{[1
]}

机构：

[1] Univ Fed Santa Maria, Dept Surg, BR-97050600 Santa Maria, RS, Brazil

来源：

OBESITY SURGERY | 2007年 / 17卷 / 04期

关键词：

nesidioblastosis; gastric bypass surgery; hypoglycemia; laparoscopic distal pancreatectomy;

D O I：

10.1007/s11695-007-9096-0

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Nesidioblastosis is characterized by hyperfunction of pancreatic islets caused by hypertrophic beta cells. Postprandial symptoms of hypoglycemia are the clinical presentation of the disease. A female patient with diabetes mellitus who underwent a Roux-en-Y gastric bypass began to present postprandial symptoms of hypoglycemia. There was no radiologic (MRI) evidence of insulinoma. Selective arterial calcium-stimulation test identified hyperfunction only in the splenic artery. Laparoscopic spleen-preserving distal pancreatectomy was performed. The patient has been entirely free of any postprandial symptoms for 10 months after the partial pancreatectomy.

引用

页码：550 / 552

页数：3

共 11 条

[1] SECRETION OF GLUCAGON-LIKE PEPTIDE-1 AND REACTIVE HYPOGLYCEMIA AFTER PARTIAL GASTRECTOMY [J].

ANDREASEN, JJ ;

ORSKOV, C ;

HOLST, JJ .

DIGESTION, 1994, 55 (04) :221-228

[2] Persistent hyperinsulinemic hypoglycemia in 15 adults with diffuse nesidioblastosis -: Diagnostic criteria, incidence, and characterization of β-cell changes [J].

Anlauf, M ;

Wieben, D ;

Perren, A ;

Sipos, B ;

Komminoth, P ;

Raffel, A ;

Kruse, ML ;

Fottner, C ;

Knoefel, WT ;

Mönig, H ;

Heitz, PU ;

Klöppel, G .

AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2005, 29 (04) :524-533

[3] Minireview: Glucagon-like peptides regulate cell proliferation and apoptosis in the pancreas, gut, and central nervous system [J].

Brubaker, PL ;

Drucker, DJ .

ENDOCRINOLOGY, 2004, 145 (06) :2653-2659

[4] Postprandial GLP-1, norepinephrine, and reactive hypoglycemia in dumping syndrome [J].

Gebhard, B ;

Holst, JJ ;

Biegelmayer, C ;

Miholic, J .

DIGESTIVE DISEASES AND SCIENCES, 2001, 46 (09) :1915-1923

[5] The escalating pandemics of obesity and sedentary lifestyle - A call to action for clinicians [J].

Manson, JE ;

Skerrett, PJ ;

Greenland, P ;

VanItallie, TB .

ARCHIVES OF INTERNAL MEDICINE, 2004, 164 (03) :249-258

[6] Bariatric surgery for morbid obesity [J].

Monteforte, MJ ;

Turkelson, CM .

OBESITY SURGERY, 2000, 10 (05) :391-401

[7] Classification of hypoglycemic disorders [J].

Service, FJ .

ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA, 1999, 28 (03) :501-+

[8] Noninsulinoma pancreatogenous hypoglycemia: A novel syndrome of hyperinsulinemic hypoglycemia in adults independent of mutations in Kir6.2 and SUR1 genes [J].

Service, FJ ;

Natt, N ;

Thompson, GB ;

Grant, CS ;

van Heerden, JA ;

Andrews, JC ;

Lorenz, E ;

Terzic, A ;

Lloyd, RV .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1999, 84 (05) :1582-1589

[9] Hyperinsulinemic hypoglycemia with nesidioblastosis after gastric-bypass surgery [J].

Service, GJ ;

Thompson, GB ;

Service, FJ ;

Andrews, JC ;

Collazo-Clavell, ML ;

Lloyd, RV .

NEW ENGLAND JOURNAL OF MEDICINE, 2005, 353 (03) :249-254

[10]

SIGSTAD H, 1970, Acta Medica Scandinavica, V188, P479

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