Functionalization and cyclization reactions of 4-benzoyl-1,5-diphenyl-1H-pyrazole-3-carboxylic acid

被引：70

作者：

Akcamur, Y ^{[1
]}

Sener, A ^{[1
]}

Ipekoglu, AM ^{[1
]}

Kollenz, G ^{[1
]}

机构：

[1] GRAZ UNIV,INST ORGAN CHEM,DEPT ISOTOPE,A-8010 GRAZ,AUSTRIA

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1997年 / 34卷 / 01期

关键词：

D O I：

10.1002/jhet.5570340133

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学]; 081704 [应用化学];

摘要：

The 1H-pyrazole-3-carboxylic acid 2 or its remarkably stable acid chloride 3 can easily be converted into the corresponding ester or amide derivatives 4 or 5, respectively, from reaction with alcohols or N-nucleophiles. Pyrazolo[3,4-d]pyridazines 6a,b are obtained from cyclocondensation reactions of the pyrazoles 3 and 3, respectively, with phenylhydrazine or hydrazine hydrate, while 6c is formed in an one-pot procedure from the furan-a,3-dione 1 and hydrazine hydrate.

引用

页码：221 / 224

页数：4

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