Multiple target regulation by small noncoding RNAs rewires gene expression at the post-transcriptional level

被引：109

作者：

Papenfort, Kai ^{[1
]}

Vogel, Joerg ^{[1
]}

机构：

[1] Max Planck Inst Infect Biol, RNA Biol Grp, D-10117 Berlin, Germany

来源：

RESEARCH IN MICROBIOLOGY | 2009年 / 160卷 / 04期

关键词：

Noncoding RNAs; RNA chaperone Hfq; DsrA; RyhB; RNAIII; ABC transport systems; Iron homeostasis; Outer membrane proteins; Virulence factors; Salmonella; Stapylococcus aureus; STAPHYLOCOCCUS-AUREUS RNAIII; OUTER-MEMBRANE PROTEINS; ESCHERICHIA-COLI; MESSENGER-RNA; VIBRIO-CHOLERAE; ANTISENSE RNA; SALMONELLA-TYPHIMURIUM; DOWN-REGULATION; TRANSLATIONAL INHIBITION; COMPARATIVE GENOMICS;

D O I：

10.1016/j.resmic.2009.03.004

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Small noncoding RNAs (sRNAs), often in conjunction with Hfq protein, have increasingly been shown to regulate multiple rather than individual mRNAs, thereby reprogramming gene expression at the post-transcriptional level. This review summarizes how and when several such regulators (CyaR, DsrA, GcvB, OmrAB, RNAIII, RybB, RyhB) act upon multiple targets. (C) 2009 Elsevier Masson SAS. All rights reserved.

引用

页码：278 / 287

页数：10

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