Solid-phase luminescence determination of ciprofloxacin and norfloxacin in biological fluids

被引:17
作者
Beltyukova, S
Teslyuk, O
Egorova, A
Tselik, E
机构
[1] Odessas State Acad Food Technol, Odessa, Ukraine
[2] Natl Acad Sci Ukraine, AV Bogatsky Physchem Inst, UA-65080 Odessa, Ukraine
关键词
sensitized luminescence; ciprofloxacin; norfloxacin; zeolite; terbium (III) ion; drug analysis;
D O I
10.1023/A:1016833422299
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
A simple, rapid, and sensitive luminescence test method for the determination of ciprofloxacin (CIP) and norfloxacin (NOR) has been described. The method is based on the intramolecular energy transfer from organic acid to terbium (Tb3+) ion. Luminescence of terbium (111) complex with CIP (NOR), sorbed on the zeolite has been studied. Under optimized conditions the detection limit is I mug/mL in urine and human plasma.
引用
收藏
页码:269 / 272
页数:4
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