Epithelial calcium channel:: gate-keeper of active calcium reabsorption

被引:39
作者
Hoenderop, JGJ
Müller, D
Suzuki, M
van Os, CH
Bindels, RJM
机构
[1] Univ Nijmegen, Dept Cell Physiol, NL-6500 HB Nijmegen, Netherlands
[2] Jichi Med Sch, Dept Pharmacol, Minamimaki, Tochigi, Japan
关键词
D O I
10.1097/00041552-200007000-00003
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
The epithelial calcium channel present in the apical membrane of 1,25-dihydroxyvitamin D-3-responsive nephron segments represents the first member of a new family of calcium channels. This review covers the distinctive properties of this highly calcium-selective channel and highlights the implications for our understanding of the process of calcium reabsorption, Curr Opin Nephrol Hypertens 9:335-340. (C) 2000 Lippincott Williams & Wilkins.
引用
收藏
页码:335 / 340
页数:6
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