Artoindonesianin P, a new prenylated flavone with cytotoxic activity from Artocarpus lanceifolius

被引：49

作者：

Hakim, EH

Asnizar

Yurnawilis

Aimi, N

Kitajima, M

Takayama, H

机构：

[1] Inst Teknol Bandung, Dept Chem, Bandung 40132, Indonesia

[2] Chiba Univ, Fac Pharmaceut Sci, Inage Ku, Chiba 2638522, Japan

来源：

FITOTERAPIA | 2002年 / 73卷 / 7-8期

关键词：

Artocarpus lanceifolius; flavones; cytotoxicity;

D O I：

10.1016/S0367-326X(02)00226-5

中图分类号：

R914 [药物化学];

学科分类号：

100701 [药物化学];

摘要：

A new prenylated flavone, named artoindonesianin P (1), was isolated from the tree bark of Artocarpus lanceifolius, together with three known related compounds, artobiloxanthone (2), cycloartobiloxanthone (3) and artonol B (4). The structure of artoindonesianin P I was determined on the basis of spectral evidence (MS, H-1 and C-13 NMR) and by comparison with known related compounds. Compounds 1-4 exhibited significant cytotoxicity against murine P388 leukemia cells. (C) 2002 Elsevier Science B.V. All rights reserved.

引用

页码：668 / 673

页数：6

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