Molecular modeling of ion channels: structural predictions

被引：23

作者：

Giorgetti, A

Carloni, P

机构：

[1] SISSA, ISAS, I-34014 Trieste, Italy

[2] INFM, DEMOCRITOS Natl Simulat Ctr, I-34014 Trieste, Italy

来源：

CURRENT OPINION IN CHEMICAL BIOLOGY | 2003年 / 7卷 / 01期

关键词：

D O I：

10.1016/S1367-5931(02)00012-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Recent advances in membrane protein crystallography have greatly increased structural information of channels permeating metal ions. Structural bioinformatics techniques and molecular dynamics calculations are providing structural models of ion channels for which the three-dimensional structure is not known. Most of the reported structure prediction studies focus on K+ channels and are based on the KcsA K+ channel structure.

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收藏

页码：150 / 156

页数：7

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