Inhibition impairments in Alzheimer's disease, mild cognitive impairment and healthy aging: Effect of congruency proportion in a Stroop task

被引:120
作者
Belanger, Sara [1 ]
Belleville, Sylvie [1 ]
Gauthier, Serge [1 ]
机构
[1] Univ Montreal, Ctr Rech Neuropsychol & Cognit, Inst Univ Geriatrie Montreal, Dept Psychol,Res Ctr, Montreal, PQ H3W 1W5, Canada
关键词
Alzheimer's disease; Mild cognitive impairment; Inhibition; Aging; Stroop; Executive functions; WORKING-MEMORY CAPACITY; COLOR-WORD TEST; EXECUTIVE DYSFUNCTION; RESPONSE-INHIBITION; TEST-PERFORMANCE; OLDER-ADULTS; INTERFERENCE; DEMENTIA; AGE; ATTENTION;
D O I
10.1016/j.neuropsychologia.2009.10.021
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
010107 [宗教学]; 030301 [社会学]; 070906 [古生物学及地层学(含古人类学)];
摘要
The goal of this study was to assess inhibition and goal maintenance in persons with Alzheimer's disease, mild cognitive impairment, healthy older adults and younger adults. This was done by using a task that compared the Stroop effect in pure blocks, that comprised only incongruent trials, with the Stroop effect in mixed blocks, in which 25% of trials were incongruent and 75% were congruent (Kane & Engle, 2003). Those conditions were administered to 20 healthy younger and 20 older control participants, and to 20 participants meeting criteria for MCI and I I for AD. Results show reduced resistance to interference as a consequence of healthy aging and only partially impaired goal-maintenance capacities. Interference and goal maintenance are also impaired when comparing MCI and AD to healthy older adults, with AD suffering from a more severe impairment than MCI. In addition, there is a partial preservation of goal-maintenance capacities in MCI because reducing response speed allows them to maintain a level of error rate similar to that of healthy older adults. In contrast, AD persons suffer from a complete breakdown of goal-maintenance capacities, as is suggested by deficits on both response time and error rates. (C) 2009 Elsevier Ltd. All rights reserved.
引用
收藏
页码:581 / 590
页数:10
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