Thalamic reticular nucleus parcellation delineated by VIP and TRH gene expression in the rat

被引:14
作者
Burgunder, JM
Heyberger, B
Lauterburg, T
机构
[1] Univ Bern, Dept Neurol, Neuromorphol Lab, Bern, Switzerland
[2] Univ Bern, Dept Clin Res, Neuromorphol Lab, Bern, Switzerland
关键词
anatomy; in situ hybridization; ventral thalamus; peptides;
D O I
10.1016/S0891-0618(99)00033-2
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The distribution of the mRNAs encoding VIP (vasoactive intestinal peptide) and TRH (thyrotropin releasing hormone) was examined in the thalamic reticular nucleus of the adult rat using hybridization histochemistry with S35-labeled oligoprobes. Low levels of TRH expression were found in a medial tier. High levels of VIP expression were found in neurons located in a lateral shell of the same portion. High levels of TRH expression were found in a tier located dorsally and in a tier located ventrally to the first one. In these regions no VIP expression could be detected. These data suggest a parcellation of this nucleus according to thr differential expression patterns of TRH and VIP. (C) 1999 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:147 / 152
页数:6
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