Hybrid Treg cells: steel frames and plastic exteriors

被引：31

作者：

Barnes, Michael J. ^{[1
]}

Powrie, Fiona ^{[1
]}

机构：

[1] Univ Oxford, Sir William Dunn Sch Pathol, Oxford OX1 3RE, England

来源：

NATURE IMMUNOLOGY | 2009年 / 10卷 / 06期

关键词：

T-H-17; CELLS; FOXP3(+); DIFFERENTIATION; RESPONSES; DISEASE;

D O I：

10.1038/ni0609-563

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

071005 [微生物学]; 100108 [医学免疫学];

摘要：

Regulatory T cells have the remarkable ability to suppress immune responses driven by different types of effector T cells. Two recent studies, documenting important functions for T-bet and IRF4 in regulatory T cells, demonstrate that this ability requires the expression of transcription factors typically associated with effector T cell function.

引用

页码：563 / 564

页数：2

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