Total Phenolics Level, Antioxidant Activities and Cytotoxicity of Young Sprouts of Some Traditional Korean Salad Plants

被引:68
作者
Chon, Sang-Uk [2 ]
Heo, Buk-Gu [3 ]
Park, Yong-Seo [5 ]
Kim, Dong-Kwan [4 ]
Gorinstein, Shela [1 ]
机构
[1] Hebrew Univ Jerusalem, Hadassah Med Sch, Dept Med Chem & Nat Prod, Sch Pharm, IL-91010 Jerusalem, Israel
[2] Chosun Univ, BI Ctr, EFARINET Co Ltd, Kwangju 501759, South Korea
[3] Naju Fdn Nat Dyeing Culture, Naju 520931, South Korea
[4] Jeonnam Agr Res & Extens Serv, Naju 520715, South Korea
[5] Mokpo Natl Univ, Dept Hort Sci, Muan 534729, South Korea
关键词
Antioxidant and anticancer properties; Methanol extracts; Salad plants; THAI MEDICINAL-PLANTS; METHANOLIC EXTRACTS; GREEN TEA; PREVENTION; VEGETABLES; APOPTOSIS; CANCER; PARTS; RISK;
D O I
10.1007/s11130-008-0092-x
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
The aim of this investigation was to study the antioxidant and anticancer activities of young sprouts of some traditional Korean salad plants. Total phenolics, antioxidant and anticancer activities of the methanol extracts from young sprouts of I I salad plants were determined. The highest amount of phenolics was found in methanol extracts of Euonymus alatus (235.7 mg kg(-1)), followed by Hypericum ascyron (197.1 mg kg(-1)), Zanthoxylum piperitum (194.1 mg kg(-1)) and Zanthoxylum schinifolium (142.5 mg kg(-1)). Methanol extracts of E. alatus, H. ascyron, and Z. piperitum at 63 mg kg-1 exhibited the highest dose-depend DPPH radical scavenging activity by 91.2, 91.2 and 83.9%, respectively. According to the MTT results, the methanol extracts from Stellaria aquatica, Eleutherococcus sessilifolrus and Z schinifolium showed the highest anticancer activities against Calu-6 (IC50< 25.0 mu gml(-1)) and from S. aquatica-the highest anticancer activities against SNU-601 (153.3 mu gml(-1)), following by E. sessilifolrus (196.7 mu gml(-1)) and Amaranthus Mangostanus (303.1 mu gml(-1)). Total phenolics were highly correlated with the DPPH, suggesting that they contribute to the antioxidant properties Of the Studied plants. In conclusion: young sprouts of Korean salad possess antioxidant and anticancer properties and could be used as a supplement to proper drugs.
引用
收藏
页码:25 / 31
页数:7
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