Viral agents as biological weapons and agents of bioterrorism

被引:69
作者
Bronze, MS
Huycke, MM
Machado, LJ
Voskuhl, GW
Greenfield, RA
机构
[1] Univ Oklahoma, Hlth Sci Ctr, Dept Med, Infect Dis Sect, Oklahoma City, OK 73190 USA
[2] Vet Adm Med Ctr, Oklahoma City, OK 73104 USA
关键词
bioterrorism; viral infections; hemorrhagic fevers; encephalitis; pulmonary and renal syndromes;
D O I
10.1097/00000441-200206000-00004
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Multiple viral agents have been classified by the CDC as potential weapons of mass destruction or agents for biologic terrorism. Agents such as smallpox, viral hemorrhagic fever viruses, agents of viral encephalitis, and others are of concern because they are highly infectious and relatively easy to produce. Although dispersion might be difficult, the risk is magnified by the fact that large populations are susceptible to these agents and only limited treatment and vaccination strategies exist. Although the risk of large-scale bioterrorism using viral agents is small, public health programs and health care providers must be prepared for this potentially devastating impact on public health.
引用
收藏
页码:316 / 325
页数:10
相关论文
共 73 条
[1]   Aftermath of a hypothetical smallpox disaster [J].
Bardi, J .
EMERGING INFECTIOUS DISEASES, 1999, 5 (04) :547-551
[2]  
Behbehani Abbas M., 1988, SMALLPOX STORY
[3]   MEDICALLY IMPORTANT ARBOVIRUSES OF THE UNITED-STATES AND CANADA [J].
CALISHER, CH .
CLINICAL MICROBIOLOGY REVIEWS, 1994, 7 (01) :89-116
[4]  
CDC, 2001, Morbidity and Mortality Weekly Report, V50, P1
[5]  
*CDCP, 1994, MMWR-MORBID MORTAL W, V43, P45
[6]  
*CDCP, INT SMALLP RESP PLAN
[7]   MECHANISM OF NEUROINVASION OF VENEZUELAN EQUINE ENCEPHALITIS-VIRUS IN THE MOUSE [J].
CHARLES, PC ;
WALTERS, E ;
MARGOLIS, F ;
JOHNSTON, RE .
VIROLOGY, 1995, 208 (02) :662-671
[8]   Cytotoxic factor-autoantibodies: possible role in the pathogenesis of dengue haemorrhagic fever [J].
Chaturvedi, UC ;
Elbishbishi, EA ;
Agarwal, R ;
Mustafa, AS .
FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY, 2001, 30 (03) :181-186
[9]   Hemorrhagic fever virus-induced changes in hemostasis and vascular biology [J].
Chen, JP ;
Cosgriff, TM .
BLOOD COAGULATION & FIBRINOLYSIS, 2000, 11 (05) :461-483
[10]   Nipah virus: A recently emergent deadly paramyxovirus [J].
Chua, KB ;
Bellini, WJ ;
Rota, PA ;
Harcourt, BH ;
Tamin, A ;
Lam, SK ;
Ksiazek, TG ;
Rollin, PE ;
Zaki, SR ;
Shieh, WJ ;
Goldsmith, CS ;
Gubler, DJ ;
Roehrig, JT ;
Eaton, B ;
Gould, AR ;
Olson, J ;
Field, H ;
Daniels, P ;
Ling, AE ;
Peters, CJ ;
Anderson, LJ ;
Mahy, BWJ .
SCIENCE, 2000, 288 (5470) :1432-1435