Iodomethane oxidation by dimethyldioxirane:: A new route to hypoiodous acid and iodohydrines

被引：29

作者：

Asensio, G ^{[1
]}

Andreu, C ^{[1
]}

Boix-Bernardini, C ^{[1
]}

Mello, R ^{[1
]}

González-Nuñez, ME ^{[1
]}

机构：

[1] Univ Valencia, Dept Quim Organ, Fac Farm, E-46100 Burjassot, Valencia, Spain

来源：

ORGANIC LETTERS | 1999年 / 1卷 / 13期

关键词：

D O I：

10.1021/ol9903281

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] The oxidation of iodomethane with dimethyldioxirane allows the generation of stable neutral solutions of hypoiodous acid in the absence of any trapping agent for iodide anion. Hypoiodous acid is trapped in situ by addition to representative olefins to give iodohydrines in good yields. The stereochemical study of the products shows the anti-stereospecific nature of the iodohydroxylation reaction.

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页码：2125 / 2128

页数：4

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